The US administration has extended its line of attack on academia from US federal research to private universities. The abuse ...

Although student mobility is being restricted in a less dramatic fashion than currently in the USA, the impact on science ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

This study highlights novel genotype-driven metabolic adaptations in PM, laying the groundwork for targeted interventions ...

MicroRNA-33a and microRNA-33b are encoded within the mammalian SREBF1 and SRBF2 genes, respectively, and both SREBF1 and ...

Phosphatidylserine (PS) is a phospholipid mainly enriched in the inner leaflet of the plasma membrane; however, its role in the nucleus remains unclear. This study describes the presence of PS in the ...

Oocytes, female germ cells that develop into eggs, are among the longest-lived cells in the animal body. Recent studies on mouse oocytes highlight unique adaptations in protein homeostasis ...

The dedifferentiation of somatic cells into a pluripotent state by cellular reprogramming coincides with a reversal of age-associated molecular hallmarks. Although transcription factor induced ...

FANCM employs a sophisticated dual recognition mechanism in genome maintenance, using distinct DNA-binding domains to identify and move around on branched DNA structures. This study reveals how FANCM ...

imageimageRNase H2 dissociates from shortened telomeres allowing the stabilization of RNA–DNA hybrids to drive repair. RNase H1 is subsequently recruited to telomeres to ensure the hybrids are ...

Algorithms that constrain metabolic network models with enzyme levels to predict metabolic activity assume that changes in enzyme levels are indicative of flux variations. However, metabolic flux can ...

CAR T-cell therapy may lead to secondary malignancies, posing challenges to current pharmacovigilance concepts.