KEY POINTS Public awareness regarding the importance of disclosing and managing conflicts of interest (COIs) during the development of clinical practice and public health guidelines is growing, owing ...

Recommendation The Canadian Task Force on Preventive Health Care recommends against instrument-based depression screening using a questionnaire with cut-off score to distinguish “screen positive” and ...

Background: Fragility fractures are a major health concern for older adults and can result in disability, admission to hospital and long-term care, and reduced quality of life. This Canadian Task ...

KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department.[1][1] It is a clinical spectrum of ...

BACKGROUND: Vaccine injections can cause acute pain and distress in infants, which can contribute to dissatisfaction with the vaccination experience and vaccine hesitancy. We sought to compare the ...

Background: A resurgence of pertussis cases among both vaccinated and unvaccinated people raises questions about vaccine effectiveness over time. Our objective was to study the effectiveness of the ...

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Outbreaks of Oropouche virus infections are occurring in South America and the Caribbean Since late 2023, new outbreaks have been reported in Bolivia, Brazil, Peru, and Cuba, including among ...

Since the last Canadian acne guideline was published in 2000, 17 evidence for multiple additional treatments has been published. Thus, there was an unmet need for an updated, systematically developed, ...

Although further research evaluating “microdosing” with buprenorphine–naloxone is certainly needed (we found only 2 case reports and 1 small case series), 4, 5 adoption of this prescribing approach ...

Methods The Canadian Task Force on Preventive Health Care is an independent panel of clinicians and methodologists that makes recommendations about clinical manoeuvres aimed at primary and secondary ...

Background: Cancer surveillance data are essential to help understand where gaps exist and progress is being made in cancer control. We sought to summarize the expected impact of cancer in Canada in ...