Investors focus on the Fed's policy decision and Chair Jerome Powell's news conference. Earnings from Meta and Microsoft are due after the closing bell.

The S&P 500 closed lower Wednesday as the Federal Reserve left interest rates unchanged, even as two policymakers dissented—the first double dissent since 1993—highlighting growing divisions over the future of monetary policy.

Broadcom stock rallied 2% to hit a new high, while Palantir gained 0.4%, bouncing back from Monday's losses. Tesla skidded more than 1%, as it still tries to regain its 50-day moving average. And Uber stock steered 2.5% lower, threatening to breach its own 50-day line for the first time since late April.