USA TODAY readers have spoken – and they want a third party in US politics. But is Elon Musk the one to lead it?

Phase 1 results demonstrate that SUL-238, a first-in-class, orally administered, mitochondria-directed drug candidate, is ...

Parents and schools brace for Indiana’s new reading law, which may hold back more third graders—just as summer school funding ...

Economy gym, built in 1922 as a community center, has long outlived the high school in Wayne County community.

Its unclear how much money has been raised so far to continue Indiana's Dolly Parton Immagination Library program but signups ...

Injuries to Jayson Tatum, Tyrese Haliburton and Damian Lillard shifted the Earth in the Eastern Conference. Here's how it ...

After a shooting left his brother in critical condition and a bullet in his spine, James Holder says he now wants to move after neighbor's arrest.

If Hoosiers spent the same share of our economy on public higher education as we did in 2010, it'd mean an additional $660 ...

Across Indianapolis, construction crews seem to be everywhere, working on projects that will improve life for residents and ...

Purdue's Birck Boilermaker Golf Complex will host the PGA Junior Championships this week, with 312 of the nation's best ...

Democrats notched a big win with their recruitment of Roy Cooper for the open Senate seat being vacated by Republican Sen. Thom Tillis.

The Department of Justice is scrutinizing how battleground states manage voter rolls, focusing on removing ineligible voters.