Researchers at Imperial College London have discovered that an unusual DNA structure could be key to reversing chemotherapy resistance in ovarian cancer, one of the deadliest cancers affecting women ...

Breakthrough in cancer treatment: Study reveals DNA repair protein structure, paving way for targeted cancer drugs RAD52 has already shown promise as a drug target.

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Seeing the unseen: New method reveals 'hyperaccessible' window in freshly replicated DNA Date: January 21, 2025 Source: Gladstone Institutes Summary: A team has unearthed new findings about what ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

To develop a hybrid AI pipeline that predicts three-loop G4 structures from sequence by extending AlphaFold’s sequence-to-structure functionality with a specialized deep learning model trained on ...