The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes ...

Breakthrough molecular movie reveals DNA's unzipping mechanism with implications for viral and cancer treatments Date: March 20, 2025 Source: University of Leicester Summary: Scientists have ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug ...

Researchers have now uncovered the role of mitochondrial transcription elongation factor in maintaining the balance between mtDNA transcription and replication.

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer.

More information: Tyler M. Maclay et al, The DNA replication checkpoint targets the kinetochore to reposition DNA structure-induced replication damage to the nuclear periphery, Cell Reports (2025).